TA-CRSD-001

Clinical Research Using
Secondary Health Data

From Database Extraction to Statistical Analysis and Publication-Ready Reporting

Target audience: Clinical doctors, residents, fellows, public health practitioners, epidemiologists, medical researchers, and healthcare professionals.

6 WeeksDuration
OnlineDelivery
StataPrimary Statistical Software
$149$79Course Fee
Software and Tools: Stata Google BigQuery SQL R Course Fee: $149 $79

Course Overview

Healthcare professionals generate and encounter important clinical questions every day. Yet many have limited practical training in how to transform those questions into well-designed studies using existing health databases.

This program equips healthcare professionals with practical skills to conduct secondary-data research using real-world clinical, epidemiological, population health, and cancer datasets. Participants will learn how to formulate research questions, identify appropriate databases, extract relevant data, construct study cohorts, prepare analytical datasets, conduct statistical analyses in Stata, interpret findings, and prepare research reports and manuscripts.

The training focuses on practical research workflows rather than software demonstrations alone. Participants will work through guided examples inspired by real research questions in critical care, cardiovascular disease, diabetes, mental health, cancer epidemiology, healthcare utilization, and population health.

The program introduces databases such as NHANES, NAMCS, NHAMCS, MIMIC-IV, SEER, TCGA, CuratedMetagenomicData Repository, Canadian Community Health Survey (CCHS) Public-Use Microdata, and CDC WONDER, with additional datasets introduced where appropriate. Participants will learn that each database has its own structure, documentation, sampling design, access requirements, and analytical considerations.

The central goal is to help participants move from a research question to a defensible, reproducible analysis and a well-structured research report.

Course Fee
Original Price $149
Current Price $79
  • Duration: 6 Weeks
  • Delivery: Online, instructor-led practical training
  • Primary statistical software: Stata
  • Additional tools: Google BigQuery, SQL, and R for selected data extraction and preparation workflows
Enroll Now

Software licenses, third-party cloud charges, and fees associated with restricted data access are not included in the course fee unless expressly stated during enrollment.

Why This Course Matters in the AI Era

Artificial intelligence can help researchers brainstorm questions, explain statistical concepts, draft code, and improve manuscript language. However, AI-generated outputs are not automatically methodologically correct, reproducible, or suitable for clinical research.

Researchers still need to know how to select an appropriate dataset, define a valid study population, identify the correct variables, handle missing data, choose suitable statistical methods, assess potential bias, and interpret results in their clinical context.

These skills are especially important when working with complex health surveys, longitudinal clinical records, and restricted-access databases. For example, NHANES analyses must account for appropriate sampling weights and survey design when making population-level inferences. MIMIC-IV access and data use are also governed by specific credentialing and data-use requirements.

This course helps participants develop the judgment to use AI as a supporting tool while retaining responsibility for their data, methods, statistical results, and scientific conclusions.

The objective is not simply to produce a manuscript faster. It is to produce research that is more transparent, reproducible, and scientifically defensible.

Six-Week Curriculum

Week 1
Week 2
Week 3
Week 4
Week 5
Week 6
Topics covered
  • Introduction to secondary-data research in medicine and public health.
  • Cross-sectional, retrospective cohort, and other observational study designs.
  • Defining populations, exposures, outcomes, covariates, and time windows.
  • Developing focused research questions and testable hypotheses.
  • Assessing feasibility, novelty, and the availability of required variables.
  • Introduction to NHANES, NAMCS, NHAMCS, MIMIC-IV, SEER, CDC WONDER, and other relevant datasets.
  • Understanding codebooks, data dictionaries, documentation, and eligibility criteria.
  • Data access, research ethics, privacy, and responsible data use.
Practical activity

Participants develop a research question and identify a suitable database, the variables required, the target population, and the proposed study design.

Expected output

A concise research concept and preliminary analysis plan.

Topics covered
  • Navigating official data portals and identifying the correct files or tables.
  • Downloading and importing eligible public-use datasets.
  • Understanding relational database structures and linked tables.
  • Introduction to SQL for querying large clinical datasets.
  • Using Google BigQuery for eligible MIMIC-IV data access and extraction.
  • Introduction to R for selected data retrieval, transformation, and preparation tasks.
  • Identifying patient encounters, index dates, follow-up periods, and relevant clinical measurements.
  • Applying inclusion and exclusion criteria.
  • Documenting cohort selection and creating a reproducible extraction workflow.
  • Understanding credentialing, permissions, and restrictions on sharing data.
Practical activity

Participants follow a guided extraction workflow using an appropriate public-use dataset or authorized clinical database environment.

Expected output

A documented extraction workflow and a preliminary study cohort.

Note: Access to restricted databases such as MIMIC-IV is subject to individual approval and applicable data-use agreements. Participants without access will use approved training materials and suitable alternative datasets for the relevant exercises.

Topics covered
  • Importing data into Stata.
  • Understanding observations, variables, labels, formats, and data types.
  • Merging and appending files.
  • Recoding categorical and continuous variables.
  • Creating derived variables and clinically meaningful categories.
  • Identifying duplicate records and inconsistent values.
  • Exploring missing-data patterns and deciding how to handle missing observations.
  • Assessing outliers and implausible clinical values.
  • Checking units, time intervals, and measurement definitions.
  • Creating a clean analytical dataset.
  • Maintaining a reproducible record of data preparation decisions.
Practical activity

Participants prepare a dataset for analysis, document exclusions and recoding decisions, and run data-quality checks.

Expected output

A cleaned analytical dataset with documented preparation steps.

Topics covered
  • Descriptive statistics for clinical and population health research.
  • Frequency distributions, means, medians, proportions, and measures of variability.
  • Comparing groups and selecting appropriate statistical tests.
  • Confidence intervals, p-values, and effect estimates.
  • Correlation and association analysis.
  • Linear regression and logistic regression.
  • Confounding, covariate selection, and adjusted estimates.
  • Interpreting odds ratios, regression coefficients, and confidence intervals.
  • Introduction to survival analysis and time-to-event outcomes where appropriate.
  • Survey-weighted analysis for suitable datasets such as NHANES.
  • Creating publication-quality tables and figures.
  • Using Stata do-files to make analyses reproducible.
Practical activity

Participants analyze their prepared dataset using a structured Stata workflow, select suitable statistical methods, and interpret the results.

Expected output

A reproducible Stata analysis file and an initial set of results tables.

Topics covered
  • Translating statistical output into meaningful clinical and public health findings.
  • Distinguishing statistical significance from clinical importance.
  • Interpreting adjusted and unadjusted associations.
  • Understanding bias, confounding, uncertainty, and limitations in observational research.
  • Assessing whether the data support the conclusions being drawn.
  • Preparing clear tables, graphs, and figures.
  • Writing the methods and results sections.
  • Structuring the discussion around the study findings and existing evidence.
  • Selecting appropriate reporting guidelines for the study design.
  • Using AI to assist with explanations, organization, and language while independently verifying every analytical claim.
  • Maintaining transparency and avoiding unsupported causal conclusions.
Practical activity

Participants develop a results narrative and draft the methods and results sections of their research report.

Expected output

A structured analytical report with tables, figures, and an interpretation of findings.

Topics covered
  • Structuring an original research manuscript.
  • Writing the title, abstract, introduction, methods, results, and discussion.
  • Aligning research objectives, statistical methods, tables, and conclusions.
  • Reporting study limitations and generalizability.
  • Preparing references and supplementary analytical materials.
  • Documenting statistical methods and reproducibility.
  • Understanding journal selection, submission requirements, and peer review.
  • Identifying common reporting weaknesses that can affect manuscript quality.
  • Preparing a final research presentation.
Practical activity

Participants consolidate their work into a final research report or draft manuscript and present their research workflow, methods, and principal findings.

Expected output

A completed capstone research report or manuscript draft, accompanied by the relevant analytical code and supporting tables or figures.

Software and Tools

Stata: Core Statistical Analysis Tool

Stata is the required primary statistical analysis environment for this program. Participants will use it for data management, descriptive statistics, hypothesis testing, regression analysis, relevant survey-weighted procedures, selected survival analyses, visualization, and reproducible reporting.

Google BigQuery and SQL: Clinical Data Extraction

Participants will be introduced to SQL-based querying and Google BigQuery for appropriate large clinical datasets, particularly eligible MIMIC-IV data hosted in BigQuery.

R: Selected Data Preparation Workflows

R will be introduced where useful for accessing, transforming, or preparing data from particular sources. The course does not aim to train participants as general-purpose R programmers.

The emphasis is on selecting the appropriate tool for each stage of the research workflow while retaining Stata as the central environment for statistical analysis.

Software note: A licensed Stata installation is recommended. Software licenses, third-party cloud charges, and fees associated with restricted data access are not included in the course fee unless expressly stated during enrollment.

Databases Covered

The main teaching examples will draw from the following databases, subject to data availability and access requirements:

NHANES

Health examination, laboratory, nutrition, and population health research.

NAMCS

Physician office visits, prescribing patterns, and ambulatory care.

NHAMCS

Emergency department and hospital outpatient research.

MIMIC-IV

Critical care, hospital outcomes, and clinical cohort studies.

SEER

Cancer incidence, stage, survival, and disparities.

CDC WONDER

Mortality trends and public health surveillance.

NHIS and BRFSS

Health conditions, behaviors, and healthcare access.

MEPS

Healthcare utilization, expenditures, insurance, and access.

The course will prioritize a manageable number of complete workflows rather than attempt to cover every database in equal depth. Additional databases may be introduced through demonstrations and supplementary materials.

Learning Objectives

By the end of the program, participants should be able to:

  1. 1Translate a clinical or public health problem into a focused, answerable research question.
  2. 2Identify appropriate secondary health databases for different research objectives.
  3. 3Navigate database documentation, codebooks, variable dictionaries, and data-use requirements.
  4. 4Extract relevant data using appropriate methods, including SQL queries in Google BigQuery and selected R-based workflows where applicable.
  5. 5Define inclusion and exclusion criteria and construct reproducible study cohorts.
  6. 6Clean, merge, recode, and prepare data for statistical analysis.
  7. 7Identify and assess missing data, outliers, and data-quality concerns.
  8. 8Conduct descriptive and inferential statistical analyses using Stata.
  9. 9Apply appropriate regression models and, where relevant, survey-weighted or survival analyses.
  10. 10Interpret effect estimates, confidence intervals, p-values, and model results in clinical and public health contexts.
  11. 11Create clear tables, figures, and analytical summaries for research reports.
  12. 12Prepare a structured research report or draft manuscript based on an applied project.
  13. 13Use AI responsibly to support research workflows without delegating scientific judgment or compromising restricted data.

Who Should Enroll?

This course is designed for:

  • Clinical doctors and medical specialists interested in conducting original research.
  • Residents, fellows, and postgraduate medical trainees.
  • Public health practitioners and epidemiologists.
  • Clinical researchers and academic faculty.
  • Healthcare professionals interested in retrospective cohort studies and cross-sectional analyses.
  • Researchers who want to strengthen their statistical analysis and manuscript preparation skills.
  • Professionals who have clinical research ideas but need a structured workflow for analyzing existing health data.

Participants do not need to be experienced programmers. Basic familiarity with research concepts and a willingness to engage in practical exercises are recommended.

Training Methodology

The program combines instructor-led demonstrations, guided practical exercises, case-based discussions, assignments, and a final applied project.

Participants will learn through research questions similar to those encountered in clinical and public health practice, including:

Factors associated with uncontrolled hypertension among adults receiving treatment.

Associations between medication use and metabolic outcomes.

Predictors of clinical outcomes among critically ill patients.

Cancer stage, treatment patterns, and survival.

Healthcare utilization and socioeconomic disparities.

Associations between lifestyle factors and chronic disease outcomes.

These are illustrative training topics. Final project feasibility depends on the available variables, dataset documentation, sample size, and study design.

Course Duration and Delivery

Duration: Six weeks.

The program is designed for working healthcare professionals and can be delivered through scheduled online practical sessions, guided assignments, demonstrations, and access to supporting learning materials.

The final timetable and weekly session schedule will be communicated before the cohort begins.

Expected Deliverables

By the end of the program, each participant who completes the required coursework should have developed:

1

A research question and analysis plan.

2

A documented data extraction and cohort selection workflow.

3

A cleaned analytical dataset or an appropriately documented dataset-preparation workflow.

4

A reproducible Stata do-file.

5

Statistical results tables and figures.

6

An interpretation of findings and limitations.

7

A structured research report or draft manuscript.

The final output depends on the selected dataset, project scope, and participant progress. Journal acceptance or publication is not guaranteed.

Assessment and Certificate

Assessment will be based on practical assignments, participation in guided exercises, and completion of the capstone project.

Participants who satisfy the Academy's completion and assessment requirements will receive a certificate of completion from Trakanalytica Academy.

Why Train With Trakanalytica Academy?

Trakanalytica Academy focuses on practical analytics, statistical reasoning, research methods, and the application of analytical tools to real-world problems.

The course is informed by practical experience supporting clinical research projects across multiple areas of medicine and public health. Its focus is on helping healthcare professionals understand the complete analytical process, from identifying the right data to interpreting the results and presenting findings responsibly.

You will not simply learn which commands to run. You will learn why particular analytical decisions matter, how to assess the quality of your findings, and how to document the work so that other researchers can understand and evaluate it.

Enroll Today

Have a clinical research question you want to investigate? Want to strengthen your ability to analyze existing health datasets and prepare a research report?

Join Clinical Research Using Secondary Health Data and develop practical skills for evidence-based clinical and public health research.

Original price$149
Current price$79

Practical Skills. Real-World Data. Professional Growth.